| |
Human Phenotyping Core |
PI |
1. |
Premier Maintenance Trial (WLM - Weight Loss Maintenance) |
Dr. Phillip Brantley |
2. |
Preventing Obesity-Diet Strategies (POUNDS Lost) |
Dr. George Bray |
3. |
Study of Health Outcomes of Weight Loss (Look AHEAD) |
Dr. George Bray |
4. |
Post-DPP Follow-up Study (DPP-OS) |
Dr. George Bray |
5. |
Chromium and Insulin Action |
Dr. William Cefalu |
6. |
Impact of Diet on Intramyocellular Lipid, Endurance Performace and Insulin Senistivity |
Dr. Enette Larson-Meyer |
7. |
Diet, Genetics and CVD Risk Factor in Blacks (Get READI) |
Dr. Michael Lefevre |
8. |
Metabolic Adaption - Two-year Caloric Restriction (CALERIE) |
Dr. Eric Ravussin |
9. |
Fat Cell Size, Muscle Lipid Infiltration & Insulin Resistance |
Dr. Eric Ravussin |
10. |
Determinants of Human Longevity and Healthy Aging |
Dr. Eric Ravussin |
11. |
Menopause Effect on Obesity, Energy Balance and Insulin |
Dr. Steven Smith |
12. |
Wise Mind: Environmental Approach for Obesity Prevention |
Dr. Donald Williamson |
13. |
Obesity: From Genes to Man |
Dr. Phillip Brantley |
|
Molecular Mechanisms Core |
PI |
1. |
The Agouti-Related Protein and its Role in Human Obesity |
Dr. George Argyropoulos |
2. |
Heritage Family Study, Phase 4: The Genomics Center |
Dr. Claude Bouchard |
3. |
Melancortin-3 Receptor Regulation of Insulin Action |
Dr. Andrew Butler |
4. |
Chromium and Insulin Action |
Dr. William Cefalu |
5. |
Control of Gene Transcription by Essential Fatty Acids |
Dr. Thomas Gettys |
6. |
The Role of Delta-6 and Delta-5 Desaturases |
Dr. Thomas Gettys |
7. |
Circadian Mechanisms Regulating Osteogenesis |
Dr. Jeffrey Gimble |
8. |
Molecular Genetics of Thermogenesis |
Dr. Leslie Kozak |
9. |
Genetics of Developmental Plasticity in the Adipocyte |
Dr. Leslie Kozak |
10. |
Novel Regulation of Adipogenesis: Agouti and Melanocortins |
Dr. Randall Mynatt |
11. |
Role of Poly (ADP-ribosyl) Action in Diabetic Neuropathy |
Dr. Irina Obrosova |
12. |
Gene-Genetics, Fitness, Obesity, and Risk of Hypertension |
Dr. Tuomo Rankinen |
13. |
Metabolic Adaptation - Two-year Caloric Restriction (CALERIE) |
Dr. Eric Ravussin |
| 14. |
Fat Cell Size, Muscle Lipid Infiltration & Insulin Resistance |
Dr. Eric Ravussin |
| 15. |
Positional Candidate Gene Analysis for Macronutrient Selection QTL |
Dr. Brenda Richards-Smith |
| 16. |
Molecular Mechanism of IKK in FFA-associated Insulin Resistance |
Dr. Jianping Ye |
| 17. |
Enterostatin Regulation of Fat Intake |
Dr. Andrew Butler |
| 18. |
Obesity: From Genes to Man |
Dr. Phillip Brantley |
| 19. |
Polygenic Regulation of Murine Obesity |
Dr. Aamir Zuberi |
|
Animal Models and Phenotyping Core |
PI |
1. |
The Agouti-Related Protein and its Role in Human Obesity |
Dr. George Argyropoulos |
2. |
Autonomic Regulation of Food Intake and Metabolism |
Dr. Hans-Rudolf Berthoud |
3. |
Dietary Obesity |
Dr. George Bray |
4. |
Melancortin-3 Receptor Regulation of Insulin Action |
Dr. Andrew Butler |
5. |
Control of Gene Transcription by Essential Fatty Acids |
Dr. Thomas Gettys |
6. |
The Role of Delta-6 and Delta-5 Desaturases |
Dr. Thomas Gettys |
7. |
Molecular Genetics of Thermogenesis |
Dr. Leslie Kozak |
8. |
Novel Regulation of Adipogenesis: Agouti and Melanocortins |
Dr. Randall Mynatt |
9. |
Role of Poly (ADP-ribosyl) Action in Diabetic Neuropathy |
Dr. Irina Obrosova |
10. |
Positional Candidate Gene Analysis for Macronutrient Selection QTL |
Dr. Brenda Richards-Smith |
11. |
Brainstem Esophageal - Gastric Control Reflexes |
Dr. Richard Rogers |
12. |
TNF, Vagal Tone and Gastric Motility |
Dr. Richard Rogers |
13. |
Molecular Mechanism of IKK in FFA-associated Insulin Resistance |
Dr. Jianping Ye |
| 14. |
Enterostatin Regulation of Fat Intake |
Dr. Andrew Butler |
| 15. |
Obesity: From Genes to Man |
Dr. Phillip Brantley |
| 16. |
Polygenic Regulation of Murine Obesity |
Dr. Aamir Zuberi |
